Cytohubba stress

WebDec 3, 2024 · The gene network was analyzed using 12 scoring methods available in Cytohubba - betweenness, bottleneck, closeness, clustering coefficient (CC), degree, density of maximum neighborhood component (DMNC), eccentricity (EcC), edge percolated component (EPC), maximal clique centrality (MCC), maximum neighborhood component … WebMar 15, 2024 · CytoHubba, which has been widely used to explore important nodes in biological networks, was then applied to identify the lip and oral cavity carcinoma hub proteins in the PPI network. ... The PI3K/Akt pathway is a central controller of viability in response to cell stress (e.g., pH, nutrient, and oxygen levels), and deregulation of the …

Frontiers Identification of Hub Genes and Their …

WebFinally, the hub genes were screened from the PPI network using the MCC algorithm of CytoHubba plugin. ... Functional enrichment analysis indicated that DEGs were mainly … WebApr 1, 2024 · The extent of drought stress is varieties and time-dependent, however, the molecular response mechanisms of drought tolerance in sunflower with different varieties are still unclear. ... CytoHubba analysis showed that the top 10 genes all encoded ribosomal proteins. Up-regulated genes were enriched in the KEGG pathway of … fix my blinds chain tensioner https://charlesandkim.com

Frontiers Identification of oxidative stress-related genes and ...

WebThe CYBA gene provides instructions for making a protein called the cytochrome b-245 alpha chain (also known as p22-phox). This protein is one part (subunit) of a group of … WebJan 4, 2024 · The Cytoscape plugin cytoHubba was applied to identify hub genes from the PPI network. Connectivity value and stress methods were used to identify hub genes. Significant clusters were generated by using PEWCC (version 1.0) . Significant transcription factors (TFs) were screened by generating the TF-gene network. WebNov 26, 2024 · The target of RA was screened based on Comparative Toxicogenomics Database (CTD). The key genes were output by the four algorithms' maximum neighborhood component (MNC), degree, maximal clique centrality (MCC), and stress in cytoHubba in Cytoscape, while biological functions and pathways were also analyzed. fixmyblinds.com coupon

Frontiers Integrative analyses of biomarkers and pathways for ...

Category:Identification of potential candidate genes for lip and oral cavity ...

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Cytohubba stress

WGCNA combined with machine learning algorithms for analyzing …

WebDec 8, 2014 · CytoHubba provides 11 topological analysis methods including Degree, Edge Percolated Component, Maximum Neighborhood Component, Density of Maximum … WebThe plug-in CytoHubba (version 1.6) in Cytoscape was used to explore significant genes in the PPI network, and the genes with most interactions were referred as hub genes, which might play core roles in the disease pathogenesis. 17 We used Maximal Clique Centrality (MCC) to calculate the hub genes. Results Identification of DEGs

Cytohubba stress

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WebAug 8, 2024 · Twelve methods in cytoHubba (Betweenness, BottleNeck, Closeness, Clustering Coefficient, Degree, DMNC, EcCentricity, EPC, MCC, MNC, Radiality, and Stress) were used to rank and evaluate the hub genes, and to finally generate the hub gene network; DAVID was used for hub gene enrichment analysis of GO, and KEGG further … WebAug 6, 2024 · After conducting WGCNA, a total of 45 potential hub genes were identified. Lu et al. used CytoHubba MCC method in their study to screen out hub genes, whereas …

WebJan 1, 2024 · CytoNCA and cytoHubba were performed and identified overlapping DEGs. In addition, we narrowed down DEGs by filtering with immune-related genes and identified … WebNational Center for Biotechnology Information

WebMar 18, 2024 · The top 20 hub genes were calculated using the seven algorithms of the plug-in CytoHubba ... Closeness, Radiality, Stress, and EPC) were used in evaluating and selecting hub genes.

WebOct 3, 2024 · The results demonstrate that baicalin may exert anti-oxidative stress effects by targeting NOX4, providing new mechanisms and insights to baicalin for the treatment …

WebApr 30, 2024 · HCC is hard to diagnose and has a poor prognosis due to the less understanding of the molecular pathological mechanisms and the regulation … fix my bissell carpet cleanerWebApr 11, 2024 · In addition, the MCC module in the Cytohubba plugin filtered the top 20 hub genes in each of the three datasets and then took the intersection of the top 20 hub genes to determine the common hub genes by Venn software, ... (ASK1) by histone modifications in sufficient cells induces oxidative stress to reduce glomerular injury. Bioinformatics ... cannaweed ace seedWebMar 4, 2024 · A plugin named cytoHubba was introduced to screen hub genes of PPI network in Cytoscape. CytoHubba can provide 12 topological analysis methods including Betweenness, BottleNeck, Closeness, Clustering Coefficient, Degree, DMNC, EcCentricity, EPC, MCC, MNC, Radiality and Stress based on shortest paths . Results. Normalization … canna wellness - alpharettaWebMar 18, 2024 · The top 20 hub genes were calculated using the seven algorithms of the plug-in CytoHubba ... Closeness, Radiality, Stress, and EPC) were used in evaluating … cannaweis pansWebDec 7, 2024 · STRING, Cytoscape, MCODE and Cytohubba were used to construct a protein-protein interaction (PPI) network and screen key EP-DEGs. Key EP-DEGs levels … cannaweb.infoWebMar 14, 2024 · Stress cardiomyopathy (SCM) is a transient reversible left ventricular dysfunction that more often occurs in women. ... CRP, ALB, APOE, APOB, MFGE8, GAPDH, and PLAT, finally utilizing the cytoHubba plug-in to determine APOE, MFGE8, ALB, APOB, SAA1, A2M, and C3 as the hub gene, as shown in Figure 8 and Table 4. … cannawelt gmbhWebThe target genes in the PPI network were identified with the cytoHubba plugin of Cytoscape. Here, the common algorithms (MCC, MNC, EPC, Degree, Closeness, Stress, and Radiality) were used to ... canna wear