Phospho-acss2
Webphospho-Acetyl Coenzyme A Carboxylase beta Ser22 antibody (PE) Size Price Qty. 100 μl. $443.80. Add to Cart. Availability. Request Lead Time; In stock and ready for quick dispatch; Usually dispatched within 2 to 3 weeks. Shipping Destination: WebTreatment with biguanides, but not isotretinoin, significantly upregulated ACSS2 gene expression in primary sebocytes and showed synergism with lipogenic activators to induce DNL genes. ... Phospho-mTOR signals were determined by absorbance at 450nm using a SpectraMax iD3 plate reader (Molecular Devices, San Jose, CA). Statistical Analysis.
Phospho-acss2
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WebSep 18, 2024 · Acetyl-CoA synthetase 2 (ACSS2) is a conserved nucleocytosolic enzyme that converts acetate to acetyl-CoA. Adult mice lacking ACSS2 appear phenotypically normal but exhibit reduced tumor burdens in mouse models of liver cancer. The normal physiological functions of this alternate pathway of acetyl-CoA synthesis remain unclear, … WebFeb 22, 2024 · Importantly, we show that ACSS2 Ser-267 phosphorylation regulates its stability by reducing polyubiquitination and degradation. ACSS2 Ser-267 is critical for OGT …
WebDownload scientific diagram Cdk5 and p35 are important for proliferation of human TT cells. A, lysates of TT cells were immunoblotted by specific antibodies of Cdk5 and p35 with variant loading ... Web(orb1096966) ACSS2 (Phospho-Ser659) Antibody Sign in or register to save this reagent to your favourites Supplier Biorbyt Host Rabbit Type Primary Clonality Polyclonal Conjugate …
WebSep 15, 2024 · The invention relates to novel compositions, combinations and methods relating to compounds which inhibit EZH2 and their uses for treating and/or preventing tumors associated with methyltransferase EZH2. More specifically the invention relates to synergistic bi-therapy compositions for use in a method of treating and/or preventing … WebSep 18, 2024 · Acss2 Deletion Protects Against Lipid Deposition and Obesity. To gain insight into the normal physiological function of ACSS2, we compared Acss2 -null mice with …
WebMar 1, 2024 · VY-3-135 is a potent, stable ACSS2 inhibitor with good bioavailability. (A) Schematic of the forward reaction catalyzed by ACSS2. (B-C) Chemical structures of VY-3-249 and VY-3-135 and IC50 determinations for inhibitors against ACSS1 (blue squares) and ACSS2 (red circles). Data points represent mean (filled shapes) and replicates (empty …
WebNov 23, 2024 · ACSS2 enables cholesterol synthesis in the cytoplasm, which is trafficked to the surface to provide mechanical tenacity. GM3-IRE1-sXBP1-ACSS2-cholesterol axis is … ipmat fitzwilliamWebMar 1, 2024 · The standard compounds, including pyruvate, lactate, alanine, acetate, succinate, glucose, palmitate, glycine, glutamate, isoleucine, valine, leucine, and … ipmat eligibility criteria 2022Web(orb1096966) ACSS2 (Phospho-Ser659) Antibody Sign in or register to save this reagent to your favourites Supplier Biorbyt Host Rabbit Type Primary Clonality Polyclonal Conjugate Unconjugated Modification Phospho (Ser659) View Product On Supplier's Website Request a Quote from Biorbyt Supplier provided information Validations None provided orb weaver spider michiganWebAcss2 −/ mice fed a chow diet (SI Appendix, Fig. S3 A–C). Taken together, these results indicate that the absence of ACSS2 im-pedes fat deposition and obesity associated with high dietary-fat intake. Acss2 Deletion Protects Against Hepatic Steatosis. Insulin resistance and hepatic steatosis are two common pathological phenotypes orb weaver spider nicky bayWebIn the nucleus, ACSS2 binds to transcription factor EB and translocates to lysosomal and autophagy gene promoter regions, where ACSS2 incorporates acetate generated from … ipmat iim indore cut offWebACSS2 / ACAS2 is a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate ... ipmat free mock testWebACSS2(Phospho-Ser659) Antibody Orders: [email protected] Support: [email protected] Catalog No: #58003 Package Size: #58003-1 100ul … ipmat indore 2021 cutoff